Michaelis-Menten

Michaelis-Menten is a kinetic model that accurately predicts the kinetic behavior of many enzymes. A common way of writing the Michaelis-Menten form is to state it as the velocity (v), where .

This is the kinetic model for an irreversible reaction with one substrate where the product has no influence on the rate of the reaction.

When the substrate concentration is much less than the Km value (the concentration at which the velocity is equivalent to half the maximal velocity), we can in three steps re- write the Michaelis-Menten as mass action kinetics.

where

When the concentration of S is much greater than Km, the observed velocity is equal to the maximum velocity.