Look through Sha et al 2003 and Goldbeter, 1991. Address the following questions. Typically, you will identify different aspects of each paper based on your experience/expertise.

1. What biological concepts and relationships are being examined? (System statements)

2. What assumptions are made?

3. How are the mechanics of the interactions described? (kinetic model)

4. What parameter values (units/unit ranges) are used?

5. What kind of experiments are performed?

6. How do the experiments relate to parts of the model?

7. What words/concepts appear critical to understanding the paper/biology/model?